Protocol: 2023_009 US MRI Combined
Open Access Status
Open AccessStable URL
https://open.oxcin.ox.ac.uk/protocols/stable/5525b837-c996-4c6f-9818-6391abf4380d
Original Creation Date
2025-May-11 21:48:07
Version
Version 1 Edit 1 @ 2025-May-11 21:48:07
Version History
- This is the latest version
- See full history
| Protocol Version | Citation | Weblink | DOI | |
| Version 1 Edit 1 | Citing this protocol: Eleanor Martin, Morgan Roberts, Ioana F Grigoras, Olivia Wright, Tulika Nandi, Sebastian W Rieger, Jon Campbell, Tim den Boer, Ben T Cox, Charlotte J Stagg, Bradley E Treeby (2025). Open WIN MR Protocol: TUS-MRI study. Zenodo. https://doi.org/10.5281/zenodo.15360988 Please also cite the first paper published using this protocol: Eleanor Martin, Morgan Roberts, Ioana F Grigoras, Olivia Wright, Tulika Nandi, Sebastian W Rieger, Jon Campbell, Tim den Boer, Ben T Cox, Charlotte J Stagg, Bradley E Treeby (2025). Ultrasound system for precise neuromodulation of human deep brain circuits; DOI https://doi.org/10.1101/2024.06.08.597305 Acknowledgements: This study was supported by the Engineering and Physical Sciences Research Council, UK (EP/P008860/1, EP/P008712/1, EP/S026371/1). The k-Plan simulations were supported by the Ministry of Education, Youth and Sports of the Czech Republic through the e-INFRA CZ (ID:90254). EM was supported by a UKRI Future Leaders Fellowship (MR/T019166/1) and in part by the Wellcome/EPSRC Centre for Interventional and Surgical Sciences (WEISS) (203145Z/16/Z). CJS was supported by a Wellcome Trust Senior Research Fellowship (224430/Z/21/Z). The Wellcome Centre for Integrative Neuroimaging is supported by core funding from the Wellcome Trust (203139/Z/16/Z and 203139/A/16/Z). This study was supported by the NIHR Oxford Health Biomedical Research Centre (NIHR203316). The views expressed are those of the authors and not necessarily those of the NHS, NIHR or the Department of Health. For the purpose of open access, the author has applied a CC BY public copyright licence to any Author Accepted Manuscript version arising from this submission. | Weblink | DOI |
Scanner
MAGNETOM 3T Prisma - Syngo VE11C-SP01
Application
In Vivo
Total Acquisition Time
0h:38m:9s
Coils
- 3T Siemens Body Coil 18ch
Project
2023_009 US MRI Combined
File Attachments
- 2023_009_US_MRI_Combined_-_Combinded_v1.7.pdf
Description
This protocol was used in a brain stimulation study where transcranial ultrasound stimulation was applied to the lateral geniculate nucleus and brain fMRI data was acquired during stimulation (online sessions) or before and after stimulation (offline sessions). The experimental design is described in more detail in the preprint "Ultrasound system for precise neuromodulation of human deep brain circuits" here: https://www.biorxiv.org/content/10.1101/2024.06.08.597305v1. Specifically, this protocol was used in the third planning session, the online sessions and the stimulation part of the offline sessions.
Keywords
brain stimulationUsage Guidance
Staffing levels: 1 x scanner operator and 2 x researcher
Scan total duration: 45 minutes
Protocol Structure
- Combined v1.7
- localiser_3plane_64ch_400fov
- ThreeDream
- t1_NOmp_ax_1p5mm_iso_FSOn_337_176sl_NormOff
- t1_mpr_ax_1p5mm_iso_FSOn_337_176sl_NormOff
- localiser_sag_loc_400fov
- bold_ep2d_3mm_PAT2_TR3s_sparce_run1
- localiser_sag_loc_400fov
- fieldmap_gre_2mm_ep2d_337fov
- bold_ep2d_3mm_PAT2_TR3s_sparce_run2
- localiser_sag_loc_400fov
- bold_ep2d_3mm_PAT2_TR3s_sparce_run3
- localiser_sag_loc_400fov
Keywords
BOLD
Acquisition Time
0h:8m:14s
Description
sparse T2*-weighted 2D EPI sequence used to acquire fMRI data during visual checkerboard presentation (voxel size 3 × 3 × 3 mm, TR=3000 ms, volume TA=2600 ms, resulting in a 400 ms idle period in each repetition)
Keywords
BOLD
Acquisition Time
0h:8m:14s
Description
sparse T2*-weighted 2D EPI sequence used to acquire fMRI data during visual checkerboard presentation (voxel size 3 × 3 × 3 mm, TR=3000 ms, volume TA=2600 ms, resulting in a 400 ms idle period in each repetition)
Keywords
BOLD
Acquisition Time
0h:8m:14s
Description
sparse T2*-weighted 2D EPI sequence used to acquire fMRI data during visual checkerboard presentation (voxel size 3 × 3 × 3 mm, TR=3000 ms, volume TA=2600 ms, resulting in a 400 ms idle period in each repetition)