Protocol: 2021_110 Lateralisation in fTCD and fMRI

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Open Access Status

Open Access Status

Open Access

Stable URL

https://open.oxcin.ox.ac.uk/protocols/stable/803258f4-3ca7-4198-ae85-4fe13cd1bbe7

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Version Info

Original Creation Date

2022-Mar-09 15:47:57

Version

Version 1 Edit 7 @ 2022-Mar-31 11:09:46

Version History

Reference List
Scanning Info

Scanner

MAGNETOM 3T Prisma - Syngo VE11C-SP01

Application

In Vivo

Total Acquisition Time

0h:11m:51s

Coils

  • 3T Siemens Head Coil 32ch
Protocol Info

Project

2021_110 Lateralization in fTCD and fMRI

File Attachments

  1. 2021_110_Lateralisation.docx

Description

This study investigates the lateralisation of language function using six different language tasks. Two methods for measuring lateralisation are compared: (1) functional transcranial doppler sonography (fTCD), and (2) functional magnetic resonance imaging (fMRI). Participants are healthy neurotypical adults who attend two sessions: in the first they perform the six tasks with fTCD and in the second they perform the tasks with fMRI. This fMRI protocol is used in the second session.

During the MRI scan, noise cancelling headphones are used to minimise the scanner noise during the language tasks. A short BOLD scan is used before the task fMRI scans to train the noise cancelling software.

The protocol includes:

- localiser

- training fMRI scan (no task)

- fMRI scan, task 1

- fMRI scan, task 2

- fMRI scan, task 3

- B0 fieldmap

- T1w structural scan

- fMRI scan, task 4

- fMRI scan, task 5

- fMRI scan, task 6.

The total scan time is around 75 minutes.

See Scan Protocol documents for additional details.

Keywords

Adult Brain fMRI Language T1

Usage Guidance

Please contact Kate Watkins (kate.watkins@psy.ox.ac.uk) to discuss re-use. Please note that Kate is unable to assist with implementation.

To cite this protocol, please use: Aikin N, Woodhead Z, Rieger SW, Semple J, Bishop D and Watkins K (2022). WIN MR Protocol: 2021_110 Lateralisation in fTCD and fMRI, Zenodo. https://doi.org/10.5281/zenodo.6400975

See Scan Protocol documents for additional details.

Protocol Structure

Protcol v1.1 → Sequence 1: localiser_3plane_32ch

Keywords

Localiser

Acquisition Time

0h:0m:14s

Description

Localiser scan

Protcol v1.1 → Sequence 2: BOLD_2p4_MB6_P1_TE30_TR800_AP

Keywords

BOLD

Acquisition Time

0h:0m:37s

Description

This short training scan is included to allow the noise cancelling software to learn the scanner noise.

Protcol v1.1 → Sequence 3: BOLD_2p4_MB6_P1_TE30_TR800_AP

Keywords

BOLD

Acquisition Time

0h:0m:37s

Description

Task 1

Protcol v1.1 → Sequence 4: BOLD_2p4_MB6_P1_TE30_TR800_AP

Keywords

BOLD

Acquisition Time

0h:0m:37s

Description

Task 2

Protcol v1.1 → Sequence 5: BOLD_2p4_MB6_P1_TE30_TR800_AP

Keywords

BOLD

Acquisition Time

0h:0m:37s

Description

Task 3

Protcol v1.1 → Sequence 6: fieldmap_2p4mm_FoV_216x216x144

Keywords

Fieldmap

Acquisition Time

0h:1m:47s

Description

Fieldmap

Protcol v1.1 → Sequence 7: t1_mpr_ax_1mm_iso_32ch_v2

Keywords

T1

Acquisition Time

0h:5m:31s

Description

Structural T1

Protcol v1.1 → Sequence 8: BOLD_2p4_MB6_P1_TE30_TR800_AP

Keywords

BOLD

Acquisition Time

0h:0m:37s

Description

Task 4

Protcol v1.1 → Sequence 9: BOLD_2p4_MB6_P1_TE30_TR800_AP

Keywords

BOLD

Acquisition Time

0h:0m:37s

Description

Task 5

Protcol v1.1 → Sequence 10: BOLD_2p4_MB6_P1_TE30_TR800_AP

Keywords

BOLD

Acquisition Time

0h:0m:37s

Description

Task 6